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To further substantiate the role of m 6 A mRNA degradation in PNT, we examined mRNA stability in Ythdf2 knockout conditions during PNT

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Without oxygen, the brain does not survive

Enzyme function is also compromised by copper deficiency, including that of copper-zinc SOD (Cu-Zn SOD), resulting in a weakened antioxidant defence system and increased vulnerability to oxidative stress, contributing to the development of atherosclerosis (103)