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Likewise, disulfidoptosis occurs due to SLC7A11 overexpression leading to excessive cystine uptake and depletion of NADPH, resulting in aberrant actin disulfide bonding, cytoskeletal disruption, and cell death, especially during glucose deprivation (145)
Porcine insulin is used as an internal standard in bovine insulin analysis to reduce the effect of the matrix, which has a close retention time but does not interfere with detection (Figure 8)
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