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Chapter 2: Metabolic control in people with diabetes and CKD As primary prevention, strict metabolic control is the most effective intervention to achieve nephroprotection, both in T1D and T2D.47 The lower the HbA1c value obtained, the lower the risk of albuminuria, as strict metabolic control decreases the risk of the onset and progression of CKD in people with diabetes
Restricting glutathione biosynthesis to the cytosol is sufficient for normal plant development.
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