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In animal models the parent compound is described as relatively short-lived in plasma but with effects persisting longer than the systemic exposure window a profile the Zagreb group attributes to its stability in the gastrointestinal lumen and to downstream signaling cascades (Sikiric et al., 2018)
The biggest risk is the lack of safety evidence
Come get a quick ondansetron (Zofran) shot in the full service Medi spa or even upgrade to an IV infusion for rehydration and add-on anti nausea medication
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