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You usually dont need to conduct clinical trials to sell dietary supplements, sometimes referred to as nutraceuticals. A second loophole involves compounding pharmacies, which are largely regulated by state pharmacy boards
However, human safety data remains limited to anecdotal reports and Phase I/II trial abstracts that never reached full peer-reviewed publication
The body is a hugely complicated & integrated system of anatomy, physiology and biochemistry
To give you a clearer picture, the table below outlines some common B12 injection schedules for different scenarios
Certain lab requirements are needed
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