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Anal Chem, 79: 8720, 2007 Smith, Phase II Metabolism, UNC Chapel Hill, 8/2012Smith, PC et al
215 Both the sufficient glycolysis and the effective oxidation of alcohol require fast reoxidation of NADH to NAD + through the coordinated reduction of pyruvate to lactate by LDH or production of ATP by mitochondrial ETC
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These enzymes are involved in the detoxification of both endogenous and exogenous electrophiles which can react with cellular components such as DNA
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