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As a result, Nrf2 escapes degradation and translocate to the nucleus, where it binds to Antioxidant Response Elements (AREs) within the promoter regions of target genes

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Beyond indirect effects, researchers have discovered that GLP-1 receptors are present on male reproductive tissuesincluding the testes (particularly on Leydig cells, which produce testosterone)frontiersin.org

Fibroblast growth factor-induced motor end plate regeneration in atrophic muscle

These findings suggest that survodutide has the potential to reduce liver fibrosis and improve liver function in patients with NASH, making it a promising therapeutic option for this complex liver disease [89]