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Blood work to evaluate thyroid function, fasting insulin, and metabolic markers can identify treatable issues
Nutritional assessment may be warranted during prolonged treatment with significant weight loss, particularly if dietary intake is severely restricted or if symptoms of deficiency develop
For instance, in the STEP 4 trial, participants who discontinued Wegovy after 20 weeks regained approximately 70% of the weight they had lost within 48 weeks
Calories, amino acids, and other components could trigger an insulin response
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