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Reported EC50 values at this receptor vary by more than an order of magnitude across papers because of receptor expression level, cell background, incubation time, albumin content of the assay medium and the reference ligand chosen
That balance is what makes this review useful
And we say likely only to account for the very slim chance that a safe, prescription-free version of DSIP is out there, somewhere on the internet
Beyond these established classes, novel agents such as dual and triple receptor agonists are currently being investigated
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