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Not only has CJC-1295 demonstrated the potential to increase growth hormone and IGF-I secretion
Not as a magic bullet
4,5 Dietary insufficiency, pernicious anemia (i.e., an autoimmune process that reduces available intrinsic factor and subsequent absorption of vitamin B 12 1,2,6,7 ), and long-term use of metformin or acid-suppressing medications have been implicated in B 12 deficiency
FOXO4-DRI represents a peptide-based senolytic approach that is more targeted than small-molecule senolytics like dasatinib plus quercetin, which affect broader cellular pathways
Biochemistry 57 , 33263337 (2018)
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