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Since the intestinotrophic effects of pharmacological GLP-1R and GLP-2R activation both require keratinocyte growth factor (KGF/ Fgf7) 15,34 and pharmacological GLP-2 also requires insulin-like growth factor-1 (IGF) action to increase villus length and small intestinal weight 52 , we measured the mRNA expression of these target genes in response to cold stress
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9 Pharmacologic approaches to glycemic treatment: standards of care in diabetes-2023
The blend may look organized and purpose-built on paper, but that packaging can suggest a level of validation that the underlying evidence does not yet provide
GLP-1 was discovered as a peptide encoded by the proglucagon gene and was named glucagon-like because the peptide was approximately 50% homologous to glucagon
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