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Human dietary cohort studies showed that replacing carbohydrates or fats with BCAAs was associated with a dose-dependent increase in cancer mortality risk (94)

The effects vary between individuals, but many people may feel benefits for several weeks depending on their needs

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However, here are some general guidelines: For individuals with a B12 deficiency, a common protocol may involve a daily dosage of 1,000 mcg for one week, followed by the same dosage once weekly, and then once per month after addressing the deficiency

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