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Underlying mechanisms contributing to cardiovascular and renal protection are at least partially different between GLP-1RAs (mainly anti-atherogenic and vascular effects) and SGLT2is (mainly systemic and intrarenal hemodynamic changes)
Steiner M, Ocran K, Genschel J, Meier P, Gerl H, et al
On a treadmill VO 2 max test (a metric of endurance), semaglutide-treated mice ran almost as long as lean control mice and much longer than untreated obese mice
Include statistics on the prevalence of compounded GLP-1s on platforms like Groupon to emphasize the scope of the issue
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