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The receptor active and inactive states exhibited similar top occupancy residues, with hydrophobic residues such as Phe, Leu, Ile, and Val enriched in both states
Administration of exendin-4 ameliorated stress-induced defecation, decreased visceral pain sensitivity and increased the serum level of anti-inflammatory cytokine: interleukin-13 in the WistarKyoto rat strain, which was considered a model for irritable bowel syndrome [116]
It plays a key role in tissue repair, cell migration, and angiogenesis
Long-term clinical trials are crucial to assess the safety and efficacy of antiangiogenic therapies in different patient populations and disease stages
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