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Such increased permeability can also stimulate immune cells such as the macrophages and dendritic cells to release inflammatory cytokines, and enhance antigen presentation for possible autoimmune conditions (Ullah et al., 2024)

The defining structural feature is a 23-membered side-chain lactam bridge

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The potential therapeutic approaches targeting gut health in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a narrative review