In addition to mock-transfected cells, each plate contained control siRNAs targeting either paxillin or cofilin-1 + destrin, as well as a cell-death inducing siRNA mixture (AllStars Hs Cell Death siRNA, Qiagen) at a final concentration of 25 nM (see Extended Data Fig
Bullock BP, Heller RS, Habener JF (1996)
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Of particular note, GLP-1 interacts with its G-protein coupled receptor, GLP-1R, to exert stimulatory action on adenylyl cyclase