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The distinction matters for one practical reason
All three RAMPs can interact with CTR, and this gives rise to three discrete Amy receptor phenotypes, AMY 1 R, AMY 2 R and AMY 3 R, with RAMP1, RAMP2, and RAMP3, respectively 7,8
Bocedi A, Fabrini R, Farrotti A, Stella L, Ketterman AJ, Pedersen JZ et al
We supplemented the crystal structure with site-directed mutagenesis to link the structural information of the isolated extracellular domain with the binding properties of the full-length receptor
The implications for people on anticoagulant therapy are complex
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