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Materials and methods Structural inspection Coordinates of the solved crystal structures of human albumin (PDB ID: 6WUW) 95 and truncated human FcRn in complex with human albumin (PDB ID: 4N0F) 52 were retrieved and inspected using PyMOL (version 2.5) (Schrdinger, Inc.)
The broader picture is that the next generation of obesity treatments involves multi-target approaches, whether through single molecules activating multiple receptors (tirzepatide, retatrutide, survodutide, mazdutide) or through combination therapies pairing separate compounds (CagriSema)
PubMed Scholar Diehn M, Cho RW, Lobo NA
The role of GSH efflux in staurosporine-induced apoptosis in colonic epithelial cells
Peer review Peer review information Nature Communications thanks Toni Giorgino and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
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