Overview of the Treatment of Hyponatremia in Adults - UpToDate (2025)
cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family
Patients with T2DM initiating GLP-1 RAs or metformin as first-line monotherapy were included (87,229 matched patients per cohort).The researchers found that compared with metformin, GLP-1 RA use was associated with a significantly lower risk for overall dementia, Alzheimer disease, and nonvascular dementias (adjusted hazard ratios, 0.90, 0.88, and 0.75, respectively)
Por lo tanto, comprender la causa es fundamental para un tratamiento adecuado
A 2018 meta-analysis found no favorable effect of DPP-4 inhibitors on all-cause mortality, cardiovascular mortality, myocardial infarction or stroke in patients with type 2 diabetes