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The HIIT + CIT group experienced significant reductions in myostatin and body fat percentage, along with improvements in muscular strength and aerobic capacity relative to the CIT-only group
Quality of life Participants using L-Carnitine showed a significant increase in their vitality score at week 8 relative to baseline ( P = 0.025)
Therefore, composite dietary fiber intervention may alleviate muscle atrophy in obesity primarily by inhibiting UPS-mediated proteolysis through the reduction of Atrogin-1 and MuRF-1 expression
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