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GLP-1 receptor agonists are a class of medications that mimic a natural hormone in your body that regulates appetite and blood sugar
When dose reduction is appropriate Phase 3 trials include provisions for dose reduction: Gastrointestinal adverse events or inadequate oral intake may warrant stepping down to a lower dose level see Retatrutide Side Effects for incidence rates by dose BMI reaching 22 kg/m or below , or perceived excessive weight loss, allows dose reduction Treatment is discontinued at BMI 18.5 kg/m or below How Often and When to Take Retatrutide Injection frequency once weekly by subcutaneous injection, on the same day each week
Also, conceivably, GLP1s may prove so successful for some patients that bariatric surgery is no longer needed
Huang T, Zhang K, Sun L, et al
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