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Overdose of B12 can cause anxiety, acne, skin redness, headache, nausea, vomiting, heart stroke, face paralysis, palpitations, facial ruddiness, and insomnia
However, levels drop when oxidative stress shoots up, such as during aging, or when you are exposed to toxins, illness, or injury
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Therefore, its best to avoid it while pregnant, trying to get pregnant, or breastfeeding
