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If homocysteine methyltransferase is defective, or if vitamin B 12 or FH 4 levels are insufficient, homocysteine will accumulate
Images were acquired using a ZEISS Axio Zoom.V16 (ZEISS, Oberkochen, Germany) stereo microscope equipped with a ZEISS PlanNeoFluar Z 1x/0.25 FWD 56 mm objective
Biol Trace Elem Res 199(11):40744083
Recent studies utilizing CRISPR screens and Perturb-map analysis have identified IL-4 as a key mediator of immune resistance, particularly in its ability to sustain an immunosuppressive niche that limits effector T cell activity
A cytosolic surveillance mechanism activates the mitochondrial UPR
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