The snRNA-seq data revealed that Ccl28 was significantly more abundant than Ccl27 in human ischemic cardiomyopathy samples and that Ccl28 was expressed in non-myocardial cells of the heart ( Fig
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It has been suggested to promote organized collagen formation, enhance fibroblast activity (cells crucial for connective tissue repair), and improve the mechanical strength of repaired tissues
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Orforglipron (Orfoglip), approved in 2025, is the newest oral GLP-1 agonist