semaglutide anhedonia Computational phenotyping of effort-based decision-making in type-2 diabetes on and off GLP-1 Agonists Are Psychiatric Drugs.

Green, R

In a phase 3, double-blind, randomized, controlled trial, 2,539 adults with a body-mass index (BMI) of 30 or greater, or 27 or greater with at least one weight-related complication, were given weekly subcutaneous injections of tirzepatide (5 mg, 10 mg, or 15 mg) or a placebo for 72 weeks

Through a collaborative partnership between its medical and data science teams, Munich Re Life US has undertaken a large-scale study to further understand the potential significance of GLP-1 drugs

The cardiovascular benefits demonstrated with GLP-1 receptor agonists such as semaglutide (in the SUSTAIN-6 and SELECT trials) cannot automatically be extrapolated to retatrutide, and direct evidence is still awaited

By delivering glutathione directly into the bloodstream or muscle tissue, patients may achieve faster absorption compared to oral supplements