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The 1998 Raun characterisation paper documented Ipamorelin's selectivity profile GH release without prolactin, ACTH, cortisol, or aldosterone elevations characteristic of earlier GHRPs (PMID 9849822)

TB-500 Defined fragment chemistry, anti-doping metabolism work and limited in vitro activity studies

Individuals with polycythemia or blood disorders These patients already have increased red cells and dont need the boost