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As, en gran medida, se reduce al mnimo cualquier posibilidad de sobredosis
The pathogenesis and the pathophysiology of sepsis is very complicated and multifaceted: numerous biological mechanisms, such as infection, inflammation, oxidative stress, immune system dysregulation, blood coagulation, endothelium dysfunction, tissue damage, elevated cellular death and/or apoptosis are involved during sepsis at tissue, cellular and molecular levels causing a damaging systemic reaction [379]
Thereafter, long-term safety considerations might favor transitioning to other medication classes based on individual response patterns and risk profiles
doi:10.1080/09637486.2016.1196655.
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