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Your ideal frequency comes down to what you're aiming for and where your levels sit now

High NNMT expression is significantly associated with unfavorable prognosis

[163], described the case of an athyreotic cretin who showed a refractoriness to high doses of desiccated thyroid when fed soybean formula due to an increased fecal concentration of 131 I-labeled levothyroxine, compared with data obtained from the same child when on a whole milk diet, thus suggesting a possible levothyroxine malabsorption