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Independent replication of some findings strengthens the evidence base
Additionally, the positive outcomes of ongoing trials SURPASS-CVOT and SURMOUNT-MMO will provide definitive evidence regarding the cardiovascular safety and efficacy of tirzepatide compared to dulaglutide and reduction in morbiditiy and mortality in adults with obesity respectively
They are generating mice in which the protein SPHKAP can be specifically deleted from -cells, allowing them to examine how disrupting this signalling hub affects pancreatic function and GLP-1R signalling
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Dementia, a condition that slowly makes it harder for people to remember things and think clearly, occurs when brain cells are damaged and their connections stop working properly
