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This is particularly concerning for a complex peptide, of which semaglutide is one

Peer review Peer review information Nature Communications thanks Nilufer Yuksel and the other anonymous reviewer(s) for their contribution to the peer review of this work

Its gastrointestinal effects stem from slowed gastric emptying and altered gut motility, not from impaired enzyme production or secretion

Sublingual is more convenient and needle-free, making it preferable for patients who cannot or will not self-inject

This is the second group of warning letters sent since a September crackdown on misleading direct-to-consumer pharmaceutical advertisements was launched following US President Donald Trumps order for tighter oversight of how companies promote prescription drugs