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In POF, the ovaries lose their germinative and hormonal functions because of the exhaustion of the number of ovarian follicles before the typical age for physiological menopause which is around 50 years of age

Samples were exposed to H 2 O 2 or buffer (blank control), and absorbance was recorded immediately at 240 nm in eight intervals ranging from 1 to 40 s

For example, women with obesity were more predisposed to severe L-C19 at one year after discharging due to hormonal, pro-inflammatory and metabolic state (176)

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doi:10.1016/j.molmet.2025.102118 4