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Days 4-7: Sleep Architecture Shifts By the end of the first week, DSIP's effects on sleep architecture are becoming more established
Some say their skin feels tender when clothing brushes against it
[13] [14] It is also worth noting that if you use hormonal contraception (such as the combined pill, progestogen-only pill, or hormonal coil), this can independently alter or suppress your bleeding pattern, which may make it difficult to distinguish any effect of weight loss medication from the effect of contraception itself
Although the pathogenesis of PCOS has not been fully elucidated, recent studies have indicated that excess levels of androgens might be the main pathogenic causative factor of PCOS (144146)
The caveat is that you need even more protein in your diet to support this increased muscle mass
