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Glutathione exists in two primary forms: the reduced form (GSH), characterized by a free sulfhydryl group (-SH) on its cysteine residue, and the oxidized form, glutathione disulfide (GSSG), which is formed when two GSH molecules are linked via a disulfide bond between their cysteine residues during redox reactions

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As the C-termini of all zDHHCs except zDHHC24 face the cytosol, we hypothesized that the addition of a C-terminal KASH-domain might induce their targeting to the ONM (Fig

Known as the body's master antioxidant, Glutathione plays a critical role in protecting cells from oxidative stress, supporting immune function and aiding in detoxification