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Interestingly, treatment withdrawal did not completely restore the mRNA transcripts, and a similar effect was observed for vitamin D metabolism genes and genes associated with NAFLD which was persistently higher, suggesting the epigenetic association between GSH deficiency and vitamin D metabolism genes
doi: 10.1177/03946320241304911 126 ChaudharyPJanmedaPDoceaAOYeskaliyevaBAbdull RazisAFModuBet al
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Pathway-level genetic context is the upstream variable underneath every protocol choice
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