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Additionally, polypharmacy, defined as the concurrent use of five or more medication classes [28], is more likely to occur in older adults and is associated with severe hypoglycemia
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Altered PER1 expression has been linked to changes in tumor behavior and sensitivity to external stressors
10.1016/j.cmet.2017.02.008 116
My advice is that any persistent change, especially heavy bleeding or cycles that restart after menopause, should always be checked with a GP or gynaecologist
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