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Moreover, functional MRI studies have demonstrated impaired connectivity within the default mode network in T2DM patients
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FIGURE 3 Another notable finding revealed by PET and NMR (nuclear magnetic resonance) spectroscopy analysis, is that in the brains of patients affected by ASD were found decreased glucose utilization and reduced ATP levels, further confirming mitochondrial dysfunction (Palmieri and Persico, 2010)
It has been reported that up to 60% of patients with lipedema have an affected first-degree relative with the same condition.8 Based on the analyses of familial clusters, in which the most affected family members are grandmothers and mothers, an autosomal dominant inheritance pattern with incomplete penetrance (sex limitation) may be suggested
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