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Safety and effectiveness of dulaglutide 0.75 mg in Japanese patients with type 2 diabetes in realworld clinical practice: 36 month postmarketing observational study
SGLT2is remained cost-effective at a threshold of AU$28,000 per QALY gained under all scenarios in the total and secondary prevention populations, except when the price of SGLT2is was set at AU$7000 (US price), when the timeframe was reduced to 20202030, and when the efficacy was reduced by 5% per year
Loading phases may run 4 to 6 weeks at the higher end of the range, followed by a maintenance dose of 1 mg/day 3 to 5 times per week
And in the STEP trials, patient-reported physical functioning improved more on the drug than on placebo (STEP patient-reported outcomes, 2024), because unloading forty pounds of fat does more for how a body moves than a modest dip in muscle takes away
