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Recently, this technique has been used to design polysuccinimide-based nanoscaffolds activated with ethylene diamine to address the decoration with oxidized EGCG (green tea polyphenol epigallocatechin-3-gallate): as a result, an improvement in the extracellular and intracellular anti-amyloidogenic effect of EGCG was detected, highlighting the potential of these nanocarriers compared to the administration of EGCG in its free molecular form in the prevention and curing of amyloid derived diseases (Debnath et al., 2016)
Adjei AA, Gaedigk A, Simon SD, Weinshilboum RM, Leeder JS: Interindividual variability in acetaminophen sulfation by human fetal liver: implications for pharmacogenetic investigations of drug-induced birth defects
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