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Lamers C
To assess the effect size of tirzepatide in resolving MetS relative to each comparator separately, we conducted 3 distinct IPD meta-analyses, each with different weights: 1 for RCTs with placebo (SURPASS-1 and SURPASS-5), 1 for RCTs with insulin (SURPASS-3, SURPASS-4, and SURPASS-AP-Combo), and 1 for RCTs with GLP-1 RA (SURPASS-2 and SURPASS J-mono) as the comparator
My protocol was straightforward: The first couple of weeks were pretty uneventful
Case presentation Four male patients were diagnosed with NAION during semaglutide treatment, with treatment durations of less than one year in three cases
The company announced results from its Phase 2b VESPER-3 study
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