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5 4) Tendon & connective-tissue pathways (GHR up-regulation) In tendon fibroblasts, BPC-157 up-regulates the growth-hormone receptor (GHR) at mRNA and protein levels and augments downstream JAK2 signaling in response to GHmechanisms consistent with tendon repair biology (in-vitro)
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Cytoprotective mechanism of the novel gastric peptide BPC157 in gastrointestinal tract and cultured enteric neurons and glial cells
Declarations Acknowledgement None
Autoantibodies and interferon- present in SLE sera enhance binding of the transcriptional repressor CREM to Gpx4 promoter, which leads to suppressed expression of GPX4 and subsequent elevation of lipid-ROS
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