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Comparison per the FDA approval submissions As seen in the table above, Wegovy and Zepbound have their advantages and disadvantages
In semaglutide trials like the STEP trials, patients on SSRIs didn't have significantly different results than patients not on SSRIs
doi: 10.1038/s41573-021-00337-8 16 WildingJBHBatterhamRLCalannaSDaviesMVan GaalLFLingvayIet al
This is most relevant at the thigh and abdomen in lean patients
The second GLP-1 agonist to reach the market [200910] was liraglutide (113), consisting of mammalian GLP-1 to which was attached a palmitic acid chain via a linker coupled to the Lys residue 26
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