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The role of the aberrant vascular endothelium in the development of cardiovascular pathologies, including atherosclerosis, ageing, hypertension, obesity, and diabetes, has been widely recognized (93)
However, the long-term effects are still under way and may not be healthy
Elderly Individuals As people age, the ability to absorb vitamin B12 from food decreases
According to a 2014 review published in The Lancet: Diabetes & Endocrinology , loss of muscle mass and strength is an important risk factor for accelerating rates of physical disability, hospitalization, and death in the older population, and is associated with the progressive health implications of diabetes, obesity, hyperthyroidism, hypercortisolism, vitamin D deficiency, osteoporosis, rheumatoid arthritis, COPD, congestive heart failure, renal disease and more
Nature Reviews Endocrinology, 9 (6), 357-365
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