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Coleman et al., 2022

For patients who have struggled with standard titration schedules or abandoned previous attempts due to intolerable side effects, this protocol offers an alternative path forward

Semaglutide can reduce hunger and support weight loss, but healthy eating and regular activity are essential

Of interest, we also observed a 6-fold increase in eNOS phosphorylation in Western blotting of isolated hearts perfused with GLP-1(2836) as compared with scramble-treated controls (Supplemental Figure 7)

Tirzepatide belongs to a class of medications called GLP-1 agonists, which were originally developed to treat type 2 diabetes