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Rengarajan A, Mullins ME
this is known as the quarter fat-free mass rule and is associated with healthy weight loss
It is most helpful for: Patients with significant appetite return after GLP-1 discontinuation Those needing a 13 month bridge while transitioning to another long-term therapy (e.g., Contrave) Individuals who previously responded well to it and tolerate stimulants Used strategically, it can help preserve momentum during treatment transitions
If flat, tighten food, increase movement
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