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GLP-1RAs have shown promising results in treating non-alcoholic fatty liver disease (NAFLD) in patients with T2DM [51]

The 2026 scoping review of dietary fibers concluded that fermentable fibers can increase endogenous GLP-1 and satiety, reinforcing a food-first approach

Similarly, semaglutide ameliorates doxorubicin-induced cardiotoxicity by reducing BNIP3-mediated mitochondrial dysfunction through the PI3K/AKT pathway, enhancing mitochondrial function and reducing cardiac injury (Li et al., 2024), potentiating its clinical application in cardiovascular diseases

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