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At 48 weeks, there was progressive decrease in weight (secondary outcome) ranging from 8.7% to 24.2% with retatrutide versus 2.1% with placebo [3]
Both medications may cause serious allergic reactions, low blood sugar (hypoglycemia), and increased heart rate
That advantage holds in compounded forms as well
On a standard insulin syringe, 1mL equals 100 units
Extended clinical trials show no evidence of organ damage from tirzepatide over 24 months, including kidney, liver, or pancreatic harm
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