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First, the demographics in this trial are not reflective of the general U.S

Most people who transition from semaglutide to tirzepatide have hit a wall of some kind, whether that wall involves stalled weight loss , persistent side effects, or simply wanting better results based on the clinical data now available

Hypoglycemia Low carnitine levels may lead to hypoglycemia, i.e., low blood glucose levels

Supports fat reduction by increasing fatty acid transport into mitochondria, L-carnitine aids lipolysis and may enhance the effectiveness of a calorie-restricted diet

Those who switched to placebo regained 6.9% of body weight nearly all they had lost in 20 weeks within the same timeframe