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Code availability No specific code was generated or used for this paper

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Additionally, patients could worsen during the study and still be classified as recovered and the study was unblinded with subjective outcomes

The conformational flexibility of TM11 appears to be linked with substrate recognition, with R471 (responsible for carnitine coordination) located near the midpoint of this helix, between the two segments that bend during the transition between inward-facing and occluded conformations

doi: 10.1126/scitranslmed.aar7047