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Significant impairment of biliary copper transport can permit copper accumulation in the liver
Imatinib-induced GPX4 proteasomal degradation Imatinib is a tyrosine kinase inhibitor designed to inhibit BCR-ABL activity in chronic myelogenous leukemia (CML) that revolutionized the treatment of this hematopoietic malignancy in the early 2000s [46]
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Nishimura J., Dewa Y., Muguruma M., Kuroiwa Y., Yasuno H., Shima T., Jin M., Takahashi M., Umemura T., Mitsumori K
Some see results in a few weeks, while others maintain therapy for long-term health and performance optimization
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