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Importantly, while RCTs consistently demonstrate robust short-term glycemic improvements, real-world data suggest that long-term treatment continuity remains a major challenge
The decrease in Nrf2 first leads to an increase of unbound Keap1, due to the reduced complex formation with Nrf2 (Fig 3C
elevated levels may indicate increased oxidative demand
Glutathione peroxidase 1 protects against peroxynitrite-induced spiral ganglion neuron damage through attenuating NF-B pathway activation
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